Lawreen H Connors Selected Research

Diflunisal (Dolobid)

9/2020	Stabilization of Cardiac Function With Diflunisal in Transthyretin (ATTR) Cardiac Amyloidosis.
1/2019	Effect of diflunisal on clusterin levels in ATTRwt amyloidosis.
10/2018	Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease.

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Lawreen H Connors Research Topics

Disease

43	Amyloidosis 09/2022 - 01/2005
18	Immunoglobulin Light-chain Amyloidosis 12/2019 - 04/2004
13	Cardiomyopathies (Cardiomyopathy) 05/2022 - 04/2004
13	Heart Failure 11/2020 - 04/2004
9	Transthyretin-Related Hereditary Amyloidosis 11/2020 - 02/2002
5	Proteostasis Deficiencies 01/2020 - 12/2007
3	Amyloid Plaque 01/2015 - 08/2008
2	Sjogren's Syndrome (Sjogren Syndrome) 05/2022 - 12/2012
2	Disease Progression 03/2018 - 11/2008
2	Cardiotoxicity 11/2014 - 07/2013
2	Polyneuropathies (Polyneuropathy) 04/2014 - 12/2008
2	Multiple Myeloma 07/2013 - 06/2005
1	Small Fiber Neuropathy 09/2022
1	Atrial Fibrillation 10/2018
1	Monoclonal Gammopathy of Undetermined Significance 03/2018
1	Familial Amyloid Neuropathies (Familial Amyloid Polyneuropathy) 11/2017
1	Plasmacytoma 06/2017
1	Pain (Aches) 01/2015
1	Hepatomegaly 01/2015
1	Heart Diseases (Heart Disease) 04/2014
1	Alzheimer Disease (Alzheimer's Disease) 04/2014
1	Mitochondrial Diseases (Mitochondrial Disease) 09/2013
1	Hypertrophy 03/2013
1	Abdominal Pain (Pain, Abdominal) 12/2012
1	Familial Amyloidosis (Hereditary Amyloidosis) 12/2012
1	Diarrhea 12/2012
1	Weight Loss (Weight Reduction) 12/2012
1	Spontaneous Rupture 01/2009
1	Septic Shock (Toxic Shock Syndrome) 01/2009
1	Peripheral Nervous System Diseases (PNS Diseases) 03/2007
1	Carpal Tunnel Syndrome 03/2007
1	Proteinuria 06/2005

Drug/Important Bio-Agent (IBA)

28	Prealbumin (Transthyretin)IBA 09/2022 - 02/2002
27	Amyloid (Amyloid Fibrils)IBA 09/2022 - 02/2002
23	Proteins (Proteins, Gene)FDA Link 05/2022 - 04/2004
15	Immunoglobulin Light Chains (Immunoglobulin Light Chain)IBA 12/2021 - 04/2004
7	Immunoglobulins (Immunoglobulin)IBA 06/2017 - 12/2007
4	ClusterinIBA 11/2020 - 01/2011
3	Diflunisal (Dolobid)FDA Link 09/2020 - 10/2018
3	Amyloidogenic ProteinsIBA 03/2018 - 08/2008
3	Blood Proteins (Serum Proteins)IBA 01/2017 - 06/2007
3	Cytidine Monophosphate (CMP)IBA 03/2013 - 11/2008
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 09/2011
2	Retinol-Binding Proteins (Retinoid Binding Proteins)IBA 03/2017 - 01/2017
2	ProteomeIBA 01/2017 - 08/2008
2	Brain Natriuretic Peptide (Natrecor)FDA Link 03/2013 - 11/2008
2	Tissue Inhibitor of Metalloproteinase-1IBA 03/2013 - 11/2008
2	Matrix Metalloproteinases (MMPs)IBA 03/2013 - 11/2008
2	Peptides (Polypeptides)IBA 08/2008 - 02/2002
1	Proline (L-Proline)FDA Link 05/2022
1	Amino Acids FDA Link 11/2020
1	Glycoproteins (Glycoprotein)IBA 11/2020
1	OligosaccharidesIBA 11/2020
1	Protein AggregatesIBA 01/2020
1	Clostridium perfringens epsilon-toxinIBA 01/2019
1	CreatinineIBA 01/2019
1	SodiumIBA 01/2019
1	Pharmaceutical PreparationsIBA 10/2018
1	Valine (L-Valine)FDA Link 03/2018
1	Isoleucine (L-Isoleucine)FDA Link 03/2018
1	Apolipoprotein A-II (Apolipoprotein A2)IBA 11/2017
1	LigandsIBA 01/2017
1	Alkaline PhosphataseIBA 01/2015
1	EnzymesIBA 01/2015
1	Sirolimus (Rapamycin)FDA Link 11/2014
1	CalciumIBA 09/2013
1	p38 Mitogen-Activated Protein KinasesIBA 07/2013
1	SB 203580IBA 07/2013
1	Troponin IIBA 03/2013
1	Metalloproteases (Metalloproteinases)IBA 03/2013
1	Muramidase (Lysozyme)IBA 12/2012
1	Biological ProductsIBA 06/2012
1	Doxycycline (Periostat)FDA LinkGeneric 12/2011
1	MicroRNAs (MicroRNA)IBA 09/2011
1	Molecular Chaperones (Chaperone, Molecular)IBA 01/2011
1	GlycosaminoglycansIBA 11/2010
1	DNA (Deoxyribonucleic Acid)IBA 10/2009
1	Melphalan (Alkeran)FDA LinkGeneric 01/2009
1	Protein Isoforms (Isoforms)IBA 08/2008
1	ApolipoproteinsIBA 08/2008
1	polyacrylamideIBA 08/2008
1	AntigensIBA 11/2007
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2004
1	Hemeproteins (Heme Protein)IBA 04/2004
1	Oxidants (Oxidizing Agents)IBA 04/2004
1	Carrier Proteins (Binding Protein)IBA 08/2003

Therapy/Procedure

7	Therapeutics 09/2022 - 04/2004
2	Lasers (Laser) 01/2017 - 08/2008
1	Organ Transplantation 05/2022
1	Drug Therapy (Chemotherapy) 01/2015
1	Aftercare (After-Treatment) 01/2009
1	Stem Cell Transplantation 01/2009